He’s a one-man crime wave.

Police yesterday said they’re looking for a suspect who’s pulled off 22 burglaries since late last month, striking small businesses all over Manhattan.

The burglar empties registers and takes electronics from upscale eateries and sandwich and pizza parlors. He’s also hit clothing boutiques and beauty salons.

The first burglary targeted Dovetail Restaurant on West 77th Street and Columbus Avenue on Nov. 20; the most recent heist was Dec. 4 at Pure Yoga on East 86th Street.