A tractor-trailer carrying two horses crashed and flipped over in the Bronx Thursday morning, killing one of the animals, police said.

A man was driving a pickup with the two horses in tow in the southbound lane of the Cross Bronx Expressway near Exit 9 in Throgs Neck shortly after 2 a.m. when he crashed into a barrier wall, causing the trailer to flip, cops said.

One of the horses was pronounced dead at the scene. Details about the second horse were not immediately available, police said.

The driver was taken to Lincoln Medical Center with minor injuries.