A squabble between two Upper West Side brothers turned deadly Thursday night, police said.

Franciso Perez, 56, allegedly plunged a knife into the torso of Luis Gonzalez, 63, at around 9:30 p.m. during a tussle at their home on West 105th street near Columbus Avenue, according to cops.

The older sibling was found lying on the floor of their first floor pad, and declared dead at the scene.

Family members told police the brothers have squared off in the past, especially when Gonzalez hit the bottle.

Cops recovered a weapon at the scene, and Perez was charged with murder, police said.

Both siblings have extensive criminal records, cops said.