A father-and-son team that owned an illegally carved-up building in which five Guatemalan immigrants died in a fire have been charged with manslaughter, Brooklyn prosecutors said yesterday.

Vasilio Gerazounis, 68, and his son, Argyrios, 37, pleaded not guilty to charges tied to the January 2010 blaze.

Daniel Ignacio, a guest of one of the doomed tenants, faces second-degree murder charges for allegedly setting the fire in a first-floor stairwell while drunk.

But DA Charles Hynes said, “The landlords share in the responsibility.”