A 19-year-old man leaped to his death Saturday from the Vessel sculpture in Hudson Yards, police said.

The tragedy, believed to be the first suicide at the climbable landmark since it opened in March, was witnessed by dozens of tourists shortly after nightfall at around 6 p.m.

Screams of horror rose from the crowd, one witness told The Post.

One witness took off his own jacket after running to the young victim, “and put it right over [the victim’s] face,” said Marita Salkowski, 50, of Kentucky.

Officials asked everyone to leave the structure, and “everybody was really quiet walking down the steps,” she said.

“Some people had tears in their eyes. My daughter and I went over to the side and said a prayer for him.”

The man, whose identity was withheld, was pronounced dead at Bellevue Hospital, according to police.