Mayoral candidate and former de Blasio legal counsel Maya Wiley took a series of sharp shots at her ex-boss during an event Thursday to launch her 2021 campaign.

“When I am mayor you will never have to wonder who is in charge,” the 56-year-old civil rights lawyer said at the campaign announcement in front of the Brooklyn Museum.

“You will never have to question whether anyone is listening, whether the mayor even wants the job. You will never have to ask yourself whether you matter.

“You’ll never have to wonder whether I’m in Iowa,” she quipped, drawing laughter from the crowd at the allusion to de Blasio’s failed 2020 presidential run when he was stuck in the Hawkeye State during a Big Apple blackout in July 2019.

She took the shots in front of her senior adviser Jon Paul Lupo, who ran de Blasio’s short-lived presidential bid. Other one-time de Blasio backers including City Hall communications staffer Alison Hirsh and pal Patrick Gaspard are also involved in Wiley’s 2021 effort.

Her reference to “whether the mayor even wants the job” seemed like a nod to de Blasio’s remarks Wednesday warning would-be mayors against running when the city is in crisis.

“I wouldn’t urge anyone to want to be mayor of New York City. It’s a very, very challenging moment,” he said at a City Hall press conference.

Wiley released a video announcing her campaign Wednesday night where she also ripped Hizzoner, by highlighting the “crisis of confidence in our city leadership.”

The married Brooklyn mom is working hard to distance herself from de Blasio, after serving as his top lawyer for two-and-a-half years from 2014 through 2016. During that time she advised the mayor on two episodes that would become major black marks on his tenure– a fundraising scandal probed by state and federal authorities and an unsuccessful effort to hide internal communications from the public and the press.

Asked by a reporter after Thursday’s announcement what she did internally to push back against some of the mayor’s controversial policies, Wiley declined to answer the question citing attorney-client confidentiality rules.

But she boasted about recommending charges against Police Officer Daniel Pantaleo for the death of Eric Garner while she was head of the Civilian Complaint Review Board in 2017 even though it would be another two years before he was fired from the NYPD.

Wiley also took credit for working with city agencies to make the Big Apple the country’s first ‘sanctuary city’ to shield illegal aliens from federal immigration policies.

“This woman stands on her own two legs,” she said when asked how she’d prove to New Yorkers that she wouldn’t follow in her predecessor’s footsteps.

If elected Wiley would be the city’s first female mayor.

She’s joined in the 2021 race by at least three other women including de Blasio’s former Sanitation Commissioner Kathryn Garcia, his ex-Veterans Services Commissioner Loree Sutton and nonprofit leader Dianne Morales. Male contenders including longtime politicians Brooklyn Borough President Eric Adams and city Comptroller Scott Stringer.