Four people were injured — two critically — in separate multiple shootings in the city overnight, police said.

The first incident happened when a gunman opened fire in Brooklyn, striking a 38-year-old man in the head and abdomen and a 32-year-old woman in the mouth, as they were standing on Pennsylvania Ave. around 10:30 p.m. Tuesday.

They were both rushed to Brookdale Hospital in critical condition.

In the Bronx, two men were shot after getting into a fight at a Prospect Avenue bar in Foxhurst around 4 a.m., police said.

When the men, 26 and 23, stepped out of the bar, the fight continued down the block.

The younger man took a bullet in the left shoulder while his friend was grazed on the left ear.

They were both treated at Lincoln Hospital for minor injuries.