Gamblers will soon be able to roll the dice in New York City.

A state board OK’d three casino licenses Monday – paving the way for the Big Apple’s first-ever Vegas-style gaming facilities that supporters say will generate billions of dollars in economic activity.

The New York Gaming Facility Location Board, tasked with approving up to three bids for potential downstate casinos, approved all three remaining finalists — two in Queens and one in the Bronx — in a 5-0 vote.

Licenses will be handed out to:

The three casinos still need a final approval from the state Gaming Commission, but they are all expected to get the greenlight barring any major developments. Each bidder is planning to build a concert hall, a hotel and offer bars and restaurants.

Each licensee has to pay a $500 million fee up front — with the total $1.5 billion to go to the Metropolitan Transportation Authority. The transit agency has already budgeted the massive income as part of its budget, anticipating the three licenses from a pool that originally included 11 bidders.

Several flashy Manhattan proposals including in Times Square and Hudson Yards were shot down or withdrawn because of community opposition.

Supporters have pushed for full gaming in the city, saying the casinos will generate billions in tax revenues and create thousands of jobs.

But the idea of Vegas-style sites in the five boroughs has had its opponents, and at Monday’s vote critics from the CUNY Graduate Center chanted “Shame! Shame!” after hearing the three licenses had been OK’d.

Grace Ying, who has lived in Flushing for more than 32 years, said she was “devastated” about the Cohen-backed casino getting the greenlight.

A spokesperson for the Cohen-backed casino in Queens said the “Metropolitan Park” project would be a home run for the area.

“They keep talking about how many jobs this will bring, but think about how many lives this will ruin,” said Ying, 65, who fought the proposal from its inception.

“Many people in my community suffer from gambling addictions, and the only thing that holds them back from throwing their money away is the distance from here to where the casinos are,” she added. “Now they won’t be able to help themselves. It’s like putting a liquor store in front of an alcoholic.”

Carla Bolden, 58, said the renderings of the casino may look “slick” but the reality would be much, much different.

“Casinos bring late-night people. They bring prostitutes. They bring drugs. They bring violence,” Bolden said, calling it “suicide” for the community.

“Casinos bring out the worst in people and they draw the worst kinds of people,” Bolden said. “I respect that it’s a big financial win for the city, but it comes at a big price as far as safety is concerned – and also the people who are going to gamble away their livelihoods.”

Cohen’s planned casino faced stiff resistance from state Sen. Sen. Jessica Ramos, who represents most of the neighborhoods along the Roosevelt Avenue corridor near the Mets ballpark and the grounds where the gaming complex would be located.

“This was never about ‘good’ or ‘bad’ jobs; it is about pursuing development that improves our quality of life, not one that increases traffic, pollution, flooding risks, addiction, and hands 78 acres of public parkland to a private interest,” Ramos said, calling casinos “predatory businesses.”

But a spokesperson for the Cohen-backed group outlined a number of economic benefits, saying the casino would be a boost for the community.

“Following a fair, transparent and rigorous process, The Gaming Facility Location Board has validated the positive economic impact this project will have with billions of dollars in tax revenue, 23,000 union jobs, and over $1 billion in community benefits,” said Metropolitan Park spokesman Karl Rickett.

Genting Group Resorts World at Aqueduct faces less resistance because it’s already been operating as a slots parlor for nearly 15 years and has developed ties with the community.

The gaming operator said it could offer live table games by the end of March, pending final approval from the state Gaming Commission. The other bidders have to build from scratch and take years to open.

“Resorts World New York City’s $7.5 billion proposal is the only bid that can expand operations in just 90 days, generating billions in new revenue for mass transit and public education over the next four years,” said Robert DeSalvio, president of Genting Americas East. “We are thankful the Gaming Facility Location Board recognized the tremendous economic impact we will have for New York State.”

Bally’s faced stiff opposition, including from local Councilwoman Kristy Marmorato, the borough’s only Republican elected official who lost her re-election bid.

Environmental activists also fought the project, claiming a casino complex would affect the water quality of the Long Island Sound.

“It is extremely disappointing that the State Gaming Facility Location Board has approved Bally’s application to develop a massive casino and hotel complex on public parkland without adequately addressing its environmental impact,” said David Ansel, vice president of the Center for Water Protection at Save the Sound.

Bally’s acquired the Trump Organization’s lease on the property before the bidding process was decided, with part of the deal requiring the buyer to fork over $115 million to the Trump Org if it won the right to operate a casino.

New Yorkers approved a referendum legalizing casino gambling in 2013. Under the law, the first four casinos were sited in economically struggling upstate communities.

The law said up to three casinos could then be licensed in the New York City downstate region.

The Gaming Commission, which has the final say on licensing, praised the working of the siting panel and strongly suggested it will license  “three impressive projects that will transform communities, establish career opportunities for residents, and drive much-needed revenue to the MTA, public schools and the City.”

“The Gaming Commission has already undertaken the background investigations of the applicants and is expeditiously applying its statutory license suitability criteria to ensure that these casinos are operated with utmost integrity and fiscal responsibility,” it said in a statement. “A New York gaming license is a privilege – and this Commission will ensure those entities fortunate enough to be selected for licensure meet New York’s rigorous standards.”