The only bird a heartbroken Upper East Side woman wants to see on Thanksgiving is her African Gray parrot, Zoe, who flew the coop a month ago during a trip to get her nails clipped.

Lois Gram, 54, is offering a $5,000 reward for the safe return of her gray and red feathered friend.

Gram thinks someone may have taken in her pet, but after weeks of searching and putting up fliers, she hasn’t heard a peep.

Zoe escaped on Oct. 24 when her plastic travel cage, strapped to a luggage carrier, hit a bump in the sidewalk on East 47th Street and Second Avenue, jarring the door open.

Gram is hoping that her generous reward in these hard times will bring back her beloved bird.

“It’s like losing a member of your family,” Gram said.