A 20-year-old man was stabbed to death allegedly by his sister after they got into a fight in his Queens home last night, cops said.

Police found Frank Fortuna with a stab wound to his neck inside 89-22 88th St. in Jamaica around 5:25 p.m. and rushed him to Jamaica Hospital where he was pronounced dead.

Cops said the sister fled following the stabbing and it is unknown whether she was accompanied by anyone else.