Two men stabbed a Manhattan straphanger after they started an argument with him on a Queens-bound E train early Sunday morning, police said.

The two suspects approached the 29-year-old victim on the train near the Lexington Avenue stop at about 12:15 a.m. and barked: “What are you looking at?” the victim told police.

One of the suspects pulled a knife and stabbed the victim once in his side, near his rib cage, authorities said.

Police responded and arrested Jacob Parker, 21 of Queens, on charges of felony assault, menacing and criminal possession of a weapon, authorities said.

The victim was taken to Cornell Medical Center and is expected to survive.

The other suspect ran out of the station and has not been arrested.