New York state’s health commissioner should resign in disgrace over the bombshell allegation that his department has under-reported nursing home deaths from COVID-19 by more than 50 percent, the top Republican in the state Senate said Thursday.

Dr. Howard Zucker committed “a gross dereliction of duty in the middle of the worst public health crisis that perhaps we have seen in our lifetime,” Senate Minority Leader Robert Ortt (R-Lockport) said.

During an afternoon conference call with reporters, Ortt called Zucker “the face of the Department of Health.”

“He is out there in all the public commercials encouraging people to get the vaccine,” Ortt said.

“How can he lead when we’ve got this report that shows he lied to the people of New York?”

Ortt also said that he and other Republicans had been seeking the data that state Attorney General Letitia James, a Democrat, released in a report earlier in the day.

“These numbers have been called for and asked for months,” Ortt said.

“That is not a missed data point. That is not an error. That is a deliberate attempt to mislead the people.”

Ortt said he “would welcome” the support of state Senate Majority Leader Andrea Stewart-Cousins (D-Yonkers) in seeking Zucker’s resignation, adding: “I certainly would encourage her and her conference to do their jobs.”

In a prepared statement, Stewart-Cousins said she was “reviewing” James’ report.

“Nothing will bring back our loved ones that we lost but it is crucial that information guides our responses so this will not happen again,” she added.

Meanwhile, another top Republican — Rep. Elise Stefanik of New York’s 22nd congressional district — declared the findings of the report exposed a “massive corruption and coverup scandal at the highest level” of state government. 

“I am calling on the New York Attorney General and the U.S. Department of Justice to issue subpoenas immediately of Governor Cuomo and his entire staff on all documentation and internal and external communications, including with any and all associations and lobbyists who have direct ties to the Governor’s senior team related to this corrupt and illegal coverup,” the pol said in a statement.

“I am committed to doing everything I can in my power to protect the independence of the ongoing federal investigation into Governor Cuomo’s nursing home disaster.”

The Department of Health didn’t immediately respond to a request for comment.