A 68-year-old woman was killed and her husband critically injured when a driver hit their car and took off in Staten Island, cops said.

The victims were in a 2009 Mercedes-Benz heading east on Lamberts Lane when a 2020 Honda driver, going north on Elson Street, rammed into them before running off around 6:20 p.m. Tuesday, police said.

The 70-year-old driver and his wife, the front-seat passenger, were both taken to Richmond University Medical Center.

The woman, identified by police as Kauser Akhund, was pronounced dead and her husband is listed in critical condition with head trauma, cops said.

The other driver was still at large Wednesday.