Jet-setting luxury real estate agents Tal and Oren Alexander and their brother used their wealth and prestige to drug and rape dozens of women they lured into their orbit for more than a decade, federal prosecutors charged Wednesday.

The two posh property bigwigs — who in 2019 helped broker the sale of a record-setting $240 million penthouse overlooking Central Park — worked with Oren’s twin Alon to use “the promise of luxury experiences, travel, and accommodations to lure and entice women to locations where they were then forcibly raped or sexually assaulted,” prosecutors allege.

“Often, the Alexander brothers drugged their victims before assaulting them, preventing them from fighting back or escaping,” the indictment said. Many of the sexual assaults involved “multiple men,” court papers state.

“This conduct, as alleged, was heinous,” US Attorney for the Southern District of New York Damian Williams said at a Manhattan news conference announcing the charges Wednesday afternoon.

The brothers arranged for some of the sexual assaults in advance by arranging meetups on dating apps and social media, and met other victims in chance encounters at nightclubs and parties, the feds said.  

Investigators believe that many of the women were drugged with the sedative GHB, which is known as the “date rape” drug, court papers said.

The brothers were arrested in and around Miami Beach Wednesday morning and were expected to make their initial court appearances in Florida. The trio were charged by the feds with conspiracy to commit sex trafficking, and sex trafficking by force, cause or coercion. The twins face separate state charges in Florida stemming from three other alleged assaults, local officials say.

The charges come after a slew of civil suits accused Oren and Alon Alexander, 37, of sickening attacks, including a claim that they took turns raping a woman inside a Hamptons castle dubbed “the Playboy Mansion of the East Coast.” Prosecutors said they’ve interviewed more than a dozen women who reported being raped by one of the brothers between 2005 and 2021.

The brothers’ depraved history of sexual violence dates back two decades to their high school days in Miami, where they bragged about several “gang rapes,” according to feds’ court filing arguing for the trio to be held without bail.

“Each of the victims that the government has interviewed from this period reported hearing that individuals involved — including Tal Alexander— talked about the assaults at school, boasting about ‘running train’ on their victims and saying they wanted to ‘do it again,’” the prosecutors wrote.

Oren even bragged about the rapes in his high school yearbook, writing that his most memorable moment was “riding my first ‘choo choo’ train,” the feds’ filing said.

Court papers also describe specifics on two alleged horrific sexual assaults. 

One victim reported being raped by Tal Alexander and other men in 2021 after being given a glass of wine at a home in The Hamptons and feeling “unwell.” The woman, referred to in court papers as Victim-1, told investigators that she recalls Tal holding her down as another man entered the room, and later being in a separate room where a camcorder was set up.

Another woman, Victim-2, reported being raped by Oren in 2016 after she “began feeling strange and struggled to walk” after Oren handed her a cocktail. Alon Alexander then took the woman to a bedroom to lay down, she recalled. She woke to find Oren in the room. Oren then pulled down her bathing suit and raped her while she was “physically impaired and could not move,” court papers alleged.

Oren and Tal Alexander, 38, co-founded the luxury real estate firm Official, which offers ritzy listings in places like New York City, the Hamptons, Miami and Los Angeles, in 2022 after rising the ranks at brokerage giant Douglas Elliman. 

Tal rents an apartment inside a skyscraper in Midtown’s famed “Billionaire’s Row,” while Oren and Alon live in “high value” properties in Miami Beach with “direct access to water” and “private docks,” the feds wrote in a court filing.

Alon has been an executive at Kent Security, a successful private security firm founded by the brothers’ parents Orly and Shlomy Alexander, but his name is not currently listed on the company’s website.

Oren’s attorney, Susan R. Necheles, told The Post Wednesday that her client is “innocent.”

“The evidence will show that neither he nor his brothers ever committed a crime,” Necheles said.

Alon’s lawyer, Isabelle A. Kirshner, and Tal’s attorney, Deanna Paul, declined to comment on the charges.

All three brothers are eventually slated to appear in Manhattan federal court, where their case has been assigned to District Judge Valerie Caproni. Each faces 15 years to life in prison if convicted.