Nick Reiner was schizophrenic, and his new medication was making him “out of his head” in the weeks before he allegedly killed Hollywood legendary dad Rob Reiner and his mom Michele, according to a report.
The iconic director’s troubled middle son, 32, was being treated by a psychiatrist for his condition — but in the month before the murders, his behavior became “alarming” as doctors switched his medication, sources told TMZ.
About three to four weeks before Rob Reiner and his wife were found stabbed to death in their Brentwood mansion, his prescription was altered, making him “erratic and dangerous,” the sources said.
Nick Reiner in Los Angeles on Sept. 9, 2025. BACKGRID
Nick Reiner, 32, allegedly killed his parents, director Rob Reiner and Michele Reiner, in their Brentwood mansion. TED SOQUI/EPA/ShutterstockDoctors were trying to adjust his medication to balance him out — but the adjustment reportedly was not working and actually made things worse, combined with his substance abuse.
Once his medication was changed, “Nick was out of his head,” a source told TMZ.
He had been receiving treatment at a ritzy Los Angeles mental health and substance abuse facility favored by the rich and powerful that charges an eye-popping $70,000 per month, according to the outlet.
Reiner was schizophrenic, and his new medication was making him “out of his head,” according to a report. FilmMagic
Reiner was arrested on Sunday, Dec. 14. LAPD Gang and NarcoticsNick Reiner, who is in custody and charged with both his parents’ murders, had struggled with drug addiction for more than half of his life and was in and out of more than a dozen rehab programs since he was 15 years old.
He allegedly fatally knifed Rob Reiner, 78, and Michele Singer, 70, sometime Sunday morning — hours after he and his father got into an ugly public shouting match at Conan O’Brien’s Christmas party.
The new schizophrenia medication made Reiner “erratic and dangerous” before the alleged murders. WireImage
Michele Singer Reiner, Rob Reiner, and Nick Reiner at Teen Vogue’s Back-to-School Saturday kick-off event at The Grove on August 9, 2013 in Los Angeles, California. Getty Images for Teen Vogue
Nick Reiner’s court sketch from his arraignment on Dec. 17, 2025. REUTERSRob Reiner’s body was discovered at around 3:40 p.m. Sunday afternoon by his daughter Romy, 28 — who did not even know that her mother was dead until paramedics also found her slain inside.
Nick Reiner was nowhere to be found, but his sister told investigators he should be considered dangerous, sources said.
Nick Reiner has been charged with the murder of his parents, Rob and Michele Reiner. Getty Images for Wynn Las Vegas
Rob and Nick Reiner hold an interview on May 4, 2016. WireImageMeanwhile, the drug addict was seen walking the streets, getting something to drink from a store and had checked in for a brief stay at a Santa Monica hotel, where investigators later found a sink covered in blood.
Nick Reiner was finally collared at a gas station the LAPD’s Gang and Narcotics Unit around 9:15 p.m. Sunday, about 15 miles from his parents’ home, dramatic video of his arrest shows.
He made his first in-person court appearance on Wednesday, showing up in a suicide vest and sporting a blank stare, only opening his mouth to utter “yes, your honor” when he waved his right to a speedy arraignment.
He is due back in court on Jan. 7 for an arraignment.
