A woman was killed, and a man was seriously injured when they were tossed from their out-of-control boat and then run over — the second fatal boating accident in Biscayne Bay in a week.

Claudia Orellanes and Neil Schwabe were thrown from the 27-foot vessel into the waters on Saturday near West Point and Crandon Park Marina, according to the Florida Fish and Wildlife Conservation Commission.

The boat then circled back around, struck them, and took off on its own.

Orellanes was pulled from the water after a short search, but died from her injuries.

Schwabe was airlifted to an area hospital, NBC Miami reported. His condition was not immediately clear.

Dramatic footage on Saturday morning’s crash obtained by the outlet shows the dual-motor boat speeding chaotically in circles with no people on board before a law enforcement officer vessel jumps in and stops it.

The deadly incident comes days after a Florida CEO was killed in a hit-and-run boat crash during an evening ride with his teenage son last Wednesday.

Davide Veglia, the founder and president of South Florida-based ABTS Convention Services, was fatally struck by the larger boat while out in Biscayne Bay just after 8 p.m.

The father-son duo was on their 7-foot dinghy in a channel off Miami Beach when the larger boat struck them, ejecting the two into the waters.

“We hear ‘Help, help!’ That’s when I run to the dock, and I see like a silhouette or like a shadow of something, and we make it out and [say], ‘That’s someone, they need help, they need help,’” Samuel Londoño told WSVN.

“We instantly called the cops, let them know everything. I yelled for him to float before the cops came, and he floated. He was, like, floating there with his dad, holding him,” Enzo Avelino recalled of the grim scene.

“The dad was unconscious when they got him and brought him back.”

The vessel is still being sought by authorities, and no arrests have been made.