The CIA struck a remote dock in Venezuela last week in the first known attack inside the South American country since the US began its months-long campaign against suspected drug traffickers in September.

The spy agency used a drone to strike the dock, believing that it was being used by the notoriously savage Venezuelan gang Tren de Aragua to load drugs onto smuggling vessels, CNN and the New York Times reported.

No one is believed to have been killed or wounded in the attack. 

However, two people were killed when a vessel was hit in the eastern Pacific on Monday — the 30th US strike since Sept 2. 

Attacks in international waters ordered by the Trump administration have killed at least 107 accused narcoterrorists.

But the dock strike represents an escalation of the president’s pressure campaign against Venezuelan dictator Nicolas Maduro, whose illegal regime was described by Secretary of State Marco Rubio as “intolerable” for the United States earlier this month.

Trump first mentioned the dock attack this past Friday and seemingly confirmed it on Monday. 

“We just knocked out — I don’t know if you read or you saw — they have a big plant, or a big facility, where the ships come from,” the president told John Catsimatidis on his WABC radio show. 

“Two nights ago, we knocked that out. So we hit them very hard.”

The strike was not public knowledge at the time of the president’s Friday remarks. It was reportedly successful in taking out the facility and its ships, but officials believe that drug traffickers have many more facilities that they use for smuggling.

“There was a major explosion in the dock area where they load the boats up with drugs,” Trump recalled to reporters at Mar-a-Lago on Monday ahead of a meeting with Israeli Prime Minister Benjamin Netanyahu.

“They load the boats up with drugs. So we hit all the boats, and now we hit the area. It’s the implementation area, that’s where they implement, and that is no longer around.”

The Venezuelan government has not commented on any attack inside its territory, by the US or anyone else.

The dock strike may not have been the only US operation targeting Venezuela, as videos posted online of an explosion at a Primazol chemical plant near Lake Maracaibo on Christmas Eve suggested it may have been the result of an American strike.

“It was empty at the time, so I don’t know if it was more like a test, just to see how we can get in and out,” a source familiar with the White House’s Venezuela strategy told The Post, adding the Trump administration is choosing to rely on “secretive” operations — at least for now.

Primazol denied the blaze was caused by a military strike, claiming in a statement that the account was “circulating on social media that seek to damage the reputation of our founder and the organization.” 

“We responsibly clarify that these claims have no relation whatsoever to the incident and are neither official nor verified,” it said.

Local official and Maduro ally Hector Soto claimed the plant fire was caused by an electrical failure while speaking to Venezuelan media.

“Let the Americans — the gringos, in this case Donald Trump and all his people — continue to dream,” said Soto, the mayor of the town where the explosions occurred. “We will defend the homeland of Bolívar.”

Two weeks ago, the president ordered a blockade of oil tankers entering and exiting Venezuela, which has the largest proven oil reserves in the world. Trump also blasted the country as a “foreign terrorist organization.”

Trump has been attempting to ramp up pressure on Venezuelan strongman Nicolás Maduro, amid Trump’s frustrations with migration and drug trafficking from the beleaguered country.

Earlier this month, the president had teased plans to hit targets inside Venezuela, but until now, his administration had not been known to have done so.

“We’re going to start doing those strikes on land, too,” Trump said earlier this month.

“The land is much easier … We know the routes they take. We know where the bad ones live.”

White House chief of staff Susie Wiles told Vanity Fair that part of Trump’s objective is to make Maduro “cry uncle.”

But Maduro, whose election victory last year has been met with international skepticism, has shown no signs of stepping aside.

Top Trump administration officials have likened the attacks against alleged Venezuelan drug traffickers to past US attacks against al Qaeda and other terrorists.

The Post contacted the CIA and White House for comment.