JD Vance slammed President Biden for calling Donald Trump supporters “garbage” — saying the commander and chief and his vice president, Kamala Harris, “ought to be ashamed of themselves.”

Trump’s running mate snapped back soon after Biden made his shocking, widely condemned comment during a campaign call at the White House Tuesday.

“A mother mourning her son who died of a fentanyl overdose is not garbage,” Vance wrote in a now-viral retort seen more than 2.4 million times by Wednesday morning.

“A truck driver who can’t afford rising diesel prices is not garbage. A father who wants to afford groceries is not garbage.

“Kamala Harris and Joe Biden ought to be ashamed of themselves,” he wrote.

Biden called Trump’s supporters “garbage” while rebuking comedian Tony Hinchcliffe for joking at Trump’s mega rally at Madison Square Garden on Sunday that Puerto Rico is a “floating island of garbage.”

“The only garbage I see floating out there is his supporters,” Biden said during a campaign call Tuesday.

President Biden’s 'garbage supporters' comment isn't the first time he’s attacked Donald Trump voters:

• “It’s not just Trump, it’s the entire philosophy that underpins the — I’m going to say something, it’s like semi-fascism.” — Joe Biden at DNC fundraiser in Bethesda, Md., on Aug. 25, 2022.

• “Donald Trump and the MAGA Republicans represent an extremism that threatens the very foundations of our republic.” — Biden at Independence Hall in Philadelphia on Sept. 1, 2022.

• “We are talking about mega MAGA Republican officials who have been very clear about this, who say, you know, they are pro-police, but then they are also pro-insurrectionists.” — Karine Jean-Pierre at press briefing on Nov. 2, 2022.

• “There is no question that today’s Republican Party is driven and intimidated by MAGA extremists. Their extreme agenda, if carried out, would fundamentally alter the institutions of American Democracy as we know it.” — Biden in Tempe, Ariz., on Sept. 28, 2023.

• “Those MAGA voices who know the truth about Trump and January 6th have abandoned the truth and abandoned our democracy.” — Biden in Blue Bell, Pa., on Jan. 5, 2024.

Earlier Tuesday night, Trump called Biden’s comment “terrible” — saying it was worse than former Secretary of State Hillary Clinton calling his supporters “deplorable” in the lead-up to the 2016 election.

In a transcript of Biden’s comments provided by the White House, his team tried to clarify there was meant to be an apostrophe in “supporters.”

“The only garbage I see floating out there is his supporter’s — his — his demonization of Latinos is unconscionable, and it’s un-American,” the transcript read.

Biden himself quickly jumped on social media to clarify the remarks.

“Earlier today I referred to the hateful rhetoric about Puerto Rico spewed by Trump’s supporter at his Madison Square Garden rally as garbage — which is the only word I can think of to describe it. His demonization of Latinos is unconscionable. That’s all I meant to say,” he wrote on X.