A key House Republican called on President Trump on Sunday to begin yanking ICE agents out of Minneapolis — warning that the chaos will only “get worse” after protester Alex Pretti was fatally shot by a federal agent a day earlier.

House Oversight Committee Chairman James Comer (R-Ky.) suggested a de-escalation was needed after the 37-year-old ICU nurse was gunned down — especially if “there’s a chance of losing more … innocent lives.”

“If I were President Trump, I would almost think about, OK, if the mayor and the governor are going to put our ICE officials in harm’s way and there’s a chance of losing more, you know, innocent lives or whatever, then maybe go to another city and let the people of Minneapolis decide, ‘Do we want to continue to have all of these illegals? Are we going to allow our governor, attorney general and mayor to get away with this?’” Comer told Fox News’ “Sunday Morning Futures.”

Elsewhere, Sens. Pete Ricketts (R-Neb.) and Bill Cassidy (R-La.) called for a full investigation into Pretti’s killing, warning that the administration’s “credibility” was at stake.

“The events in Minneapolis are incredibly disturbing. The credibility of ICE and DHS are at stake. There must be a full joint federal and state investigation. We can trust the American people with the truth,” Cassidy said in an X statement.

Ricketts described the fatal shooting as “horrifying.”

“My support for funding ICE remains the same. Enforcing our immigration laws makes our streets safer. It also protects our national security. But we must also maintain our core values as a nation, including the right to protest and assemble,” he said on X.

“I expect a prioritized, transparent investigation into this incident.”

Sen. Lisa Murkowski (R-Alaska) warned that ICE agents “do not have carte blanche in carrying out their duties.”

“Lawfully carrying a firearm does not justify federal agents killing an American — especially, as video footage appears to show, after the victim had been disarmed,” she said on X.

“A comprehensive, independent investigation of the shooting must be conducted in order to rebuild trust and Congressional committees need to hold hearings and do their oversight work.”

Outside Washington, Republican Vermont Gov. Phil Scott said in a scathing statement that it was “not acceptable for American citizens to be killed by federal agents for exercising their God-given and constitutional rights to protest their government.”

“Enough … At best, these federal immigration operations are a complete failure of coordination of acceptable public safety and law enforcement practices, training, and leadership,” said Scott.

“At worst, it’s a deliberate federal intimidation and incitement of American citizens that’s resulting in the murder of Americans. Again, enough is enough.”

Trump himself told the Wall Street Journal on Sunday that his administration was “reviewing everything” about the shooting, and will “come out with a determination.”

“I don’t like any shooting. I don’t like it,” Trump added. “But I don’t like it when somebody goes into a protest, and he’s got a very powerful, fully loaded gun with two magazines loaded up with bullets also. That doesn’t play good either.”

The president also told the outlet that federal immigration authorities would leave the Twin Cities “at some point,” with “a different group” of federal law enforcement to carry out a sweeping benefits fraud probe centered on Minneapolis’ Somali diaspora.

Trump administration officials were quick to cast Pretti as the instigator of Saturday’s bloodshed, with Homeland Security Secretary Kristi Noem among those claiming Pretti had charged at officers while armed with a gun.

Videos of the incident show several agents pinning Pretti to the ground after he put himself between the officers and a woman who had been pepper-sprayed.

The footage appears to show an agent disarming Pretti — who was licensed to carry his 9mm semi-automatic handgun concealed — moments before at least one other ICE officer opened fire on him.

Pretti’s killing has caused tension between the GOP’s long-standing support for gun rights and the Trump administration’s warnings not to disrupt immigration enforcement operations.

“Every peaceable Minnesotan has the right to keep and bear arms — including while attending protests, acting as observers, or exercising their First Amendment rights,” the Minnesota Gun Owners Caucus said in a statement.

“These rights do not disappear when someone is lawfully armed.”

The National Rifle Association added that “responsible public voices should be awaiting a full investigation, not making generalizations and demonizing law-abiding citizens.”