WASHINGTON — President Trump called on Iranian protesters to take over government buildings Tuesday in his starkest call yet for a regime-change revolution as the reported death toll from anti-government unrest soared past 2,000.

“Iranian Patriots, KEEP PROTESTING – TAKE OVER YOUR INSTITUTIONS!!!” Trump wrote on Truth Social.

“Save the names of the killers and abusers. They will pay a big price. I have cancelled all meetings with Iranian Officials until the senseless killing of protesters STOPS. HELP IS ON ITS WAY. MIGA!!!”

Hours later, Trump told CBS News anchor Tony Dokoupil in an interview that “if they hang [protesters]… we will take very strong action” — responding to reports that at least one protest participant, Erfan Soltani, 26, is set to be executed Wednesday.

“The end game is to win. I like winning,” Trump told Dokoupil.

“Well, let’s define it in Venezuela. Let’s define it with al-Baghdadi, he was wiped out. Let’s define it with Soleimani, and let’s define it in Iran, where I wiped out their Iran nuclear threat in a period of about 15 minutes.”

Trump was vague throughout the day when reporters asked about what “help” he intended to provide, saying at one point, “You’re going to have to figure that one out, I’m sorry.”

He told Dokoupil that “there’s a lot of help on the way, and in different forms, including economic help from our standpoint.”

Trump on Monday declared a trade embargo against Iran — threatening 25% tariffs on any country that fails to break off commerce — on the heels of economic concerns that sparked the ongoing unrest.

It was not immediately clear how strictly that policy would be enforced.

Iran’s top trading partners include China, Iraq, the United Arab Emirates, Turkey and India.

Trump called on American and other foreign citizens to depart Iran — as his top aides study possible military strikes. 

“I think they should get out,” Trump told reporters during a day trip to Michigan.

Trump has repeatedly threatened military action over the killings of protesters, but hasn’t tipped his hand on possible follow-through.

He previously kept secret his intentions ahead of ordering June airstrikes on Iran’s nuclear program and the Jan. 3 Delta Force raid that captured Venezuelan President Nicolas Maduro.

“If there’s one thing we’ve learned over the last six months since the 12-Day War, it’s that the president and his national security team are deliberately unpredictable,” said Dan Caldwell, former senior adviser to Secretary of War Pete Hegseth.

The president’s declaration that meetings are off with Iran, meanwhile, indicates that special envoy Steve Witkoff will not hold talks with Iranian officials who last week offered negotiations to prevent US intervention.

A small team of Trump’s senior aides, including Secretary of State Marco Rubio and Vice President JD Vance, has been preparing options since Friday and are expected to meet again Tuesday afternoon.

“They are presenting options to him ranging from a diplomatic approach to military strikes,” a source familiar with discussions told The Post. 

More than 2,000 people have been killed in Iran during the anti-government protests, according to the US-based Human Rights Activists News Agency, of whom 1,847 were protesters, and 135 were security personnel.

Trump said Tuesday that he has seen “five different sets of numbers” on the death toll, but that “it’s too many, whatever it is.”

An Iranian government-imposed internet blackout has limited circulation of images and information on the protests, which witnesses have described as morphing into slaughter.

BBC Persian described carnage across the country’s major cities — with a mortuary worker in Mashhad, Iran’s second-largest city, telling the outlet that there were 200 bodies with head injuries on Friday.

In Fardis, west of Tehran, the government’s paramilitary Basij fighters suddenly attacked protesters Friday and “two or three people were killed in every alley,” a witness told the BBC.

At a single hospital in eastern Tehran, an employee said there were roughly 40 bodies on Thursday, the British broadcaster reported.

Although Iran has seen nationwide protests before, the violence is on a scale unseen since the 1979 Islamic Revolution that toppled pro-American Shah Mohammad Reza Pahlavi and swept Ayatollah Khomeini to power.

Trump has not endorsed a particular outcome of the protests and said Thursday he did not think it was “appropriate” for him to talk to the last shah’s son, Reza Pahlavi, who has been urging on the protests.

“I think that we should let everybody go out there, and we’ll see who emerges,” the president said.