Breathtaking satellite images show Winter Storm Gail set to pound the East Coast with up to two feet of snow Wednesday.

Central Pennsylvania was forecast to be hardest hit with as much as 24 inches, according to the National Weather Service — which released an image of a swirling snow cloud covering the region.

“This will likely lead to very dangerous, if not impossible, travel conditions and isolated power outages,” the agency said Wednesday morning.

The winter storm, which includes freezing rain, will pummel areas ranging from North Carolina to Massachusetts, meteorologists said.

Meanwhile, New York City and Boston were expected to be hit with up to a foot of snow.

“Heavy snow will overtake areas northwest of I-95 in the mid-Atlantic. This means major cities, such as Washington, D.C., and Philadelphia, will likely see a wintry mix and potentially plain rain for areas just to the southeast,” the agency said.

“Further north and east, heavy snow will also encroach upon much of the Northeast and southern New England this evening, including New York City and Boston.”

As the nor’easter approached, meteorologists warned millions of people not to travel, including in parts of New Jersey, where commercial traffic was restricted on some highways starting at 1 p.m.

“Freezing rain is the main concern across this region, as upwards of a quarter-inch of ice accretion is possible,” the National Weather Service said.

Six to 12 inches of snow are expected to dump on the Big Apple starting around 4 p.m., creating an “ugly mess,” meteorologists said earlier in the day.