Law enforcement was observed Saturday night at the home of Annie Guthrie, the sister of “Today” show anchor Savannah Guthrie, as the investigation into the disappearance of her mother, Nancy Guthrie, 84, entered its seventh day.

Officers appeared to return to Annie Guthrie’s residence shortly after sheriff’s deputies were seen back at Nancy Guthrie’s home earlier the same evening, signaling continued investigative movement as the high-profile search stretched into a second week, according to Fox News Digital.

The outlet said it observed what appeared to be unmarked police vehicles at the scene. A silver briefcase was seen being removed from one of the vehicles, and white flashes were visible coming from the garage -- activity Fox News Digital described as investigators taking photographs.

Authorities have not publicly detailed the purpose of the activity or what, if anything, was recovered. The Pima County Sheriff’s Office has said the investigation remains active, with no suspects or persons of interest identified as of Saturday night.

Savannah Guthrie’s latest plea to her missing mom Nancy Guthrie’s abductor raises a chilling question, according to an expert.

On Saturday — in her second Instagram video since 84-year-old Nancy was taken from her Tucson, Ariz., home last weekend — Savannah, 54, said publicly to the kidnapper, “We received your message, and we understand.”

The “Today” show host — who was joined by sister Annie Guthrie, 56, and brother Camron Guthrie, 61 — added, “We beg you now to return our mother to us so that we can celebrate with her. This is the only way we will have peace. This is very valuable to us, and we will pay.”

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Savannah Guthrie took to social media again with an emotional video in the case of her mom, Nancy Guthrie.

“We received your message and we understand,” the “Today” anchor said, alongside her brother Camron and sister Annie.

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Savannah Guthrie eerily uttered the exact same words used in the hostage-negotiation scene from the iconic horror film “Silence of the Lambs” in the gut-wrenching video she posted earlier this week pleading for her mother’s safe return.

The “Today” show star, her sister Annie, and her brother Camron, issued a tearful video plea to their mother Nancy’s captors on Feb. 4, with Savannah sharing a pointed message.

“[Nancy] is full of kindness and knowledge. Talk to her and you’ll see,” Savannah said in a quivering voice.

A nearly verbatim message was used in Jonathan Demme’s Oscar-winning 1991 film, in a scene where a a senator is coached by the FBI to speak to the captor of her daughter in a live televised address. The goal was to get the monstrous kidnapper to see his victim as a human being.

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The Pima County Sheriff's Office said Saturday that it still has no suspects in Nancy Guthrie's apparent abduction as investigators continue to review "multiple pieces of evidence" in the sixth day of the frantic search.

"At this time, investigators have not identified any suspects, persons of interest, or vehicles connected to this case," the office said in a statement.

"This remains an active and ongoing investigation, which includes the review of multiple pieces of evidence," the statement added. "It is standard practice to seek any video available from nearby residences or businesses."

The office reiterated again that it would not hold any press conferences unless news breaks in the bewildering case.

Billboards featuring Nancy Guthrie and FBI contact details will soon appear in Arizona's neighboring states to assist in the search for the missing 84-year-old grandmother.

The billboards will be active in cities across the border region including Albuquerque, San Diego, Los Angeles, El Paso, Houston, San Antonio and Dallas, said FBI Phoenix Public Affairs Officer Brooke A. Brennan.

Billboard advertising company Clear Channel is collaborating with local authorities and the FBI, which has offered a $50,000 reward for information leading to an arrest.

Investigators are also looking into a new message related to Guthrie's disappearance that was received by a Tucson television station, though no immediate details about the message have been released.

Law enforcement officials in Arizona searching for Nancy Guthrie now have surveillance footage from a Circle K store that might have captured a “vehicle of interest” in the mystifying case, according to a report.

The car was supposedly at or near the convenience store in Tucson, according to NBC News.

A spokesperson for the store — roughly seven miles from Nancy Guthrie's house — said it has turned surveillance video over to investigators.

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A former FBI agent believes that several details surrounding Nancy Guthrie’s disappearance and her alleged abductor’s actions don’t align with a “traditional kidnapping,” as officials investigate a second message that was sent out on Friday.

“They want attention, they want the spotlight to be put on this incident,” Daniel Brunner, who worked as a special agent for 20 years, told “NewsNation Live” about the 84-year-old’s alleged captors.

Guthrie, the mother of NBC “Today” co-host Savannah Guthrie, was last seen Saturday night after hanging out at a nearby relative’s home playing games and having dinner.

She is believed to have returned to her Tucson, Ariz. home just before 9:50 p.m. Family members reported her missing just after noon Saturday.

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The feds could be closing in on a suspect in the apparent abduction of Nancy Guthrie, mom of NBC anchor Savannah Guthrie, President Trump said.

“I think we’re doing very well on everything. You’re probably surprised to hear that,” Trump told reporters on Air Force One Friday night. “We have some clues that are very strong, and I think we could have some answers coming up very soon.”

In answer to a question about a possible suspect, Trump said. “Yeah, could be definitive.”

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Law enforcement agents confiscated a SUV parked inside the garage of Nancy Guthrie’s Arizona home Friday, where they also removed a wired device from the roof after they received a tip from a neighbor.

Over 10 police cars converged on Guthrie’s residence in the Catalina Foothills north of Tucson and began searching the property in the late afternoon amid the large-scale search for the missing 84-year-old.

A tow truck was called in and removed a Blue Subaru SUV — believed to be owned by Guthrie — before police escorted the truck to an impound lot near the Pima County Sheriff’s Office, Fox News reported.

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The search for Nancy Guthrie has entered its seventh day as officials investigate the "authenticity" of a second message believed to be from the 84-year-old's captors.

"The FBI and Pima County Sheriff's Department are aware of a new message regarding Nancy Guthrie. Investigators are actively inspecting the information provided in the message for its authenticity," officials wrote on social media.

As Nancy Guthrie's abduction nightmare drags into a seventh day, "Today" show host Savannah Guthrie is desperately praying for her missing 84-year-old mother's safe return — turning to her greatest source of hope and strength: the Bible.

"On Sundays, we'd spend all day at Casas Adobes Baptist Church for Sunday school, morning service, choir practice and night service," Savannah told Guideposts, a non-denominational Christian magazine, in 2016.

"Faith was so woven into our daily lives, we liked to say that God was the sixth member of our family."

Her mother, who was taken from her Tucson, Ariz. home on Jan. 31, was a no-nonsense single mom to Savannah and her two older siblings, Camron and Annie, after husband Charles suffered a fatal heart attack in 1988.

But one day, Nancy surprised her with a spontaneously kooky quest -- and it's become one of Savannah's favorite memories.

"I was with her as she drove around doing errands," said Savannah. "There was a rare desert rainstorm and afterward, a gorgeous rainbow arced across the sky.

"'Is there really a pot of gold at the end of it?' I asked. She replied, 'I don't know. Let's find out!' With me giving instructions, we drove around laughing and chasing the elusive end of the rainbow until the last wisp of color faded."

In a poignant Feb. 2 Instagram post while praying for her mother, Savannah highlighted Isaiah 26:3 as the Biblical verse she has clung to for comfort in the midst of the family's kidnapping horror.

"He will keep in perfect peace those whose hearts are steadfast, trusting in the Lord."

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