The sheriff leading the search for Nancy Guthrie has said he "understands" why some have said her son-in-law should be seen as a suspect, but insisted he didn't want to put "a mark on somebody who could be completely innocent."

Tommaso Cioni, the husband of "Today" show co-host Savannah Guthrie's sister, Annie, was the subject of early speculation over Nancy's disappearance, due in part to being the last person known to have seen her before she vanished on Feb. 1.

Pima County Sheriff Chris Nanos said that while "nobody" has been ruled out, he was troubled by "nasty stuff" being circulated about Cioni.

"If he [Cioni] is guilty, if he's the one who did it, and we're able to prove that, then at that time jump on it, but don't come out of nowhere with this," Nanos told the Daily Mail on Sunday.

"I understand the pundits are out there. They're gonna say, well, he's the last one to see her alive. We understand that stuff. But, my goodness, you're putting a mark on somebody who could be completely innocent. And more important than that, he's family," he added.

"People out there can get pretty ugly and mean and nasty and not have the facts. I tell my journalists, you guys need to be a little more responsible … because that's just really nasty stuff," the sheriff said.

No suspects or persons of interest have been identified in Nancy's disappearance, as the hunt for the 84-year-old in Tucson, Arizona, enters its third week.

The search for "Today" show star Savannah Guthrie's mother, Nancy, has entered its third week.

Police have not made any arrests in connection with Nancy's disappearance. The FBI doubled the reward for information leading to an arrest to $100,000. They said they were going through the thousands of tips they have received.

Pima County Sheriff Chris Nanos said hundreds of officers are working to find Nancy and they have received over 30,000 calls related to the case.

The Arizona sheriff leading the search for missing Nancy Guthrie has dismissed claims that the elderly matriarch’s disappearance was the result of a burglary gone bad.

“This is somebody who disappeared from the face of the earth, and now we have a camera that says here’s the person who did this,” Chris Nanos, the Pima County Sheriff, told the Daily Mail.

Investigators are no closer to finding Nancy, 84, who has now been missing for more than two weeks. Cops have not made any arrests – despite receiving more than 40,000 tips – and have been accused of bungling the probe.

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Investigators believe that Nancy Guthrie's abduction could have been the result of a botched robbery instead of a planned kidnapping, according to a report.

An inside source in the investigation told AZFamily that the 84-year-old's kidnapping appeared to be a burglary gone wrong.

The unnamed source also told the outlet that there is a widespread belief among investigators that Nancy could still be alive.

The development comes as the investigation into Nancy's disappearance stretches into its 15th day, with her famous daughter Savannah Guthrie releasing a video to Instagram pleading with her mother's kidnapper to "do the right thing" and come forward.

Savannah Guthrie posted a new video appeal late Sunday, pleading with her mother Nancy’s alleged kidnapper that “it’s never too late” for them to “do the right thing” two weeks after she was abducted.

“I wanted to come on …  it’s been two weeks since our mom was taken and …  I just wanted to come on and say that we still have hope and we still believe,” Savannah said in an Instagram video.

“And I wanted to say that to whoever has her or knows where she is, that it’s never too late. And you’re not lost or alone, and it is never too late to do the right thing,” the “Today” TV anchor continued, pausing several times as she spoke to the camera with visible tears in her eyes.

“And we are here, and we believe in the essential goodness of every human being, and it’s never too late.”

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TUCSON, Arizona — Multiple additional gloves have been found by The Post in the same area where the FBI collected a black glove that investigators think could be tied to the abduction of Nancy Guthrie.

The Post was on the ground for the discovery of the gloves Sunday afternoon in Catalina Foothills, roughly two miles from the home of “Today” show host Savannah Guthrie’s mother.

It’s not known whether any of the discarded items are connected to the crime, but The Post has alerted the Pima County Sheriff’s Department.

All of the gloves were close enough to the highway that they could have been tossed from a speeding car.

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Nancy Guthrie authorities are able to track her pacemaker from within 800 feet using a breakthrough new bluetooth "sniffer," the creator of the technology has told The Post.

Cops have been spotted flying over the Arizona desert using an FBI scanning device that can track a working bluetooth device — in the hopes that they can home in on the pacemaker that Savannah Guthrie's mother had connected to her iPhone.

"Eight hundred feet reliably," former NSA agent David Kennedy, who is working alongside law enforcement on the case, told The Post, when asked for the range of the devices.

"Bluetooth communicates at 2.4 gigahertz, the same as all your other wireless devices. In a perfect world, where there's no wireless devices, no obstructions, and you have a line of sight, you can probably get 4,000-5,000 feet if not further," he said.

"But it's in her body, and water is a detractor from signal gain. You also have buildings and walls, interference with other 2.4 gigahertz devices as well," Kennedy, now an "ethical hacker" and CEO of TrustedSec said.

A former Marine, Kennedy hopes the device will be rolled out using drones and is working on an app that could also help find Nancy by obtaining the MAC (Media Access Control) address for her pacemaker.

"We created an Apple and iPhone app and an Android app. If we were able to get the physical address of the implantable device [the pacemaker], we could literally turn that entire community or city into scanning devices.

He said the app, which could be ready to publish "tomorrow," that, when "every single person could download on their phone and you literally hit 'Find Nancy,' and it will scan in every geographic location where they're at for that specific address and then tell the FBI, hey, there's a hit here. You need to go here to start to triangulate where it's happening.

Since Nancy Guthrie disappeared two weeks ago, law enforcement and media outlets have descended upon Tucson, Arizona — with online sleuths and podcasters following suit, much to the ire of locals.

Tucson and Pima County became ground zero for the search for the 84-year-old mother of “Today” host Savannah Guthrie — and Democratic Rep. Alma Hernandez, who represents both areas, has had enough.

“I am so sick of watching the ‘reporting’ grifting, insane speculation, lies, and BS by random wannabe journalists and YouTubers who have now caused more harm than good to this entire situation and put this serious case in jeopardy,” she seethed on X. 

“Please GO HOME. Let law enforcement do their jobs. Stop following them during swat operations and playing detectives. I am sick of the constant LIES from those who can't even spell Tucson and clearly have never been to our city. This home is not near downtown or midtown, so posting random videos of people walking in yards ain't it y'all, no, Mexicans don't all look the same, yes, our sheriff should probably stay off social media and not speak to the press anymore. Yes, this is sad, and we all want Nancy home. But seriously, PLEASE STOP,” she implored. 

The dig on Pima County Sheriff Chris Nanos came after he admitted that the case of the missing grandmother last seen on Jan. 31 was “exhausting” and it could take “years” to find her. 

The sheriff leading the search for Nancy Guthrie, mother of “Today” show host Savannah Guthrie, admitted the hunt could take “years.” Despite a massive two-week search and no suspects, the sheriff remains committed to finding Nancy, whose disappearance involved a doorbell camera and DNA evidence.

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The FBI has collected DNA from a glove found near Nancy Guthrie’s house, potentially linking it to the armed suspect seen before her disappearance. This development could provide crucial evidence from the primary suspect in the abduction of Savannah Guthrie’s mother, as investigators work to match the DNA to a national database.

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Savannah Guthrie will remain off the “Today” show for the “foreseeable future” amid the desperate hunt for her mother, Nancy Guthrie, sources tell Page Six.

The journalist, 54, is still in Tucson, Ariz., as the search for her 84-year-old mom enters the 15th day.  Unsurprisingly, this has led to rumors about her future on the NBC morning television show, where she’s been a co-anchor since July 2012.

“The entire show and network is rallying together in support of our beloved colleague and friend as we navigate this unimaginable time,” an NBC source tells Page Six. 

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Cops are flying over the Tucson desert with a high-tech Bluetooth signal detector in an attempt to locate a signal from Nancy Guthrie's pacemaker.

A Pima County Sheriff's Department helicopter has been flying in a low, slow grid pattern over the area around Nancy's home in an attempt to get a ping off the device, Fox New reported.

A helicopter was spotted flying in a similar pattern near her million-dollar house just days after she disappeared -- though it's not clear whether the whirlybird had the detector then, according to Fox.

The search for Savannah Guthrie's mom has dragged on for two weeks -- she was first reported missing Feb. 1 and last seen around 9:30 p.m. on Jan. 31.