Coast Guard rescue crews were searching for 12 missing people Wednesday off Louisiana’s coast after a large commercial vessel capsized amid high seas and winds up to 90 mph, officials said.

Coast Guard Capt. Will Watson told reporters at a press conference the body of one crew member had been recovered following Tuesday’s overturning of the 129-foot commercial lift vessel, Seacor Power, about 8 miles south of Port Fourchon in the Gulf of Mexico.

The vessel departed with a crew of 19 and later encountered extreme weather – including winds up to 90 mph and seas as high as 9 feet with “extremely limited visibility,” Watson said.

“We are saturating the area with available resources to assist in the rescue mission,” Watson said. “And we will continue to do so. As of now, we have rescued six survivors who were safely transferred ashore. Unfortunately, we recovered one individual from the surface of the water deceased, and the search effort continues for the remaining 12.”

Watson said the vessel remained overturned and partially submerged in 55 feet of water south of Port Fourchon.

A Good Samaritan reported the vessel capsizing at about 4:30 p.m. Tuesday, setting off a search and rescue mission involving private boats, Coast Guard crews and an HC-144 Ocean Sentry airplane, the Coast Guard said in a statement late Tuesday.

A crew on the 154-foot Coast Guard Cutter Glenn Harris arrived within 30 minutes and rescued one person from the ship, Coast Guard officials said.

A second Coast Guard crew pulled another person from the water, while other private vessels operated by Good Samaritans saved four people, Coast Guard officials said.

Several Coast Guard vessels, private boats and an HC-144 Ocean Sentry airplane are involved in the ongoing search for the remaining boaters.

It’s unclear exactly how many people were onboard at the time, Coast Guard spokesman Petty Officer Jonathan Lally told The Post.

“Any search and rescue is very dynamic,” Lally said early Wednesday. “But any time the Coast Guard goes out, it’s our hope that we bring them back and reunite them with their friends and family.”

Lally said it was unclear what caused the boat to capsize but noted a “microburst” of inclement weather in the area prior to the incident.

The area experienced a weather phenomenon called a “wake low” that would’ve created rough seas, NBC News reported, citing a National Weather Service meteorologist in New Orleans.

The National Oceanic and Atmospheric Administration reported wind gusts of 75 mph in nearby Grand Isle during Tuesday’s storm, according to the report.

The Seacor Power, which can carry up to 40,000-plus gallons of fuel oil, ran into trouble as a strong storm thrashed much of metro New Orleans, overturning vessels and damaging property in coastal towns, NOLA.com reported.

Asked about the potential of locating the missing 12 crewmembers alive, Watson said rescuers remained optimistic.

“Whenever we engage, the Coast Guard engages in a search and rescue effort, we are hopeful,” Watson said. “You can’t do this work if you’re not optimistic, if you’re not hopeful when you do it.”